What are the most powerful microscopes?

The best light microscope can not amplify an object more than 200 times its size. 

light microscope

The electron microscope can do it over a million times. Electromagnetic fields play the role of lenses.

electron microscope

 A heated filament sends rays of electrons, while the rest continues its journey to a screen or a photographic plate. We obtain the drop shadow of the object.

To know also:

                           Who invented the microscope?
The microscope was invented in the early seventeenth century and attributed to various inventors, including the Dutch Zacharias Jansen. What is surprising is that the lenses were known and manufactured for 300 years, but until that date nobody had thought to combine them to make either a microscope or a telescope.